Leptin is one of the best known hormone markers for obesity. There is a limited anthropometric\ndata in the Gaza Strip that reveals and arouses the nutritional status among all age groups especially\nadolescents aged 15 - 19 years old. The study aimed to assess the effect of Leptin hormone,\nlipid profiles, Body Mass Index (BMI) and waist circumference among secondary school age students\nin the Gaza Strip. Methodology: A cross sectional study included 442 cases of teenagers aged\n15 - 19 years old from governmental and private schools in the Gaza strip. Blood samples were\ncollected for analysis of Leptin hormone and lipid profile and measuring waist circumference for\nthe teenager. Results: The mean of serum Leptin was (28.7) higher among cases than controls\n(28.1), but it was statistically insignificant (P = 0.85). It was found that there is a significant correlation\nbetween Leptin hormone and total cholesterol (Chol) (r = 0.24), high density cholesterol\n(HDL) (r = 0.27) and low density cholesterol (LDL) (r = 0.16). There was no relationship between\nLeptin hormone and triglycerides (TG) (r = 0.02). There was relationship between Leptin hormone\nand waist circumference in both males and females (r = 0.519, 0.544), respectively. There\nwas no statistical significant deference noticed between Leptin hormone of obese objects and Leptin\nhormone of normal BMI objects of the same age (t-test = 0.93, P = 0.85). Conclusion: There are\nsignificant correlations between Leptin hormone and total Chol, HDL and LDL except for TG, and\nthere were significant relationships between Leptin hormone and waist circumference which reflect\nthe central obesity among males and females. There is no association between Leptin level\nand BMI.
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